Intestinal Inflammation Check with 4 markers – Verisana Lab
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Enhanced Intestinal Inflammation Check

199.00£ Incl. VAT/Sales Tax & FREE Shipping - Original Price 199.00£

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With the Enhanced Intestinal Inflammation Check, your stool sample is examined to determine:

1.) Calprotectin
2.) Lysozyme
3.) Alpha 1-Antitrypsin
4.) sIgA

All 4 are important inflammation markers ​​for your intestines and give, for example, indications of a “leaky gut”.

Availability: deliverable immediately
  • Details
  • Test measures
  • Symptoms
  • Sample collection guide
  • Sample report
  • Reviews
Details
Who should take the test?

Are you struggling with lasting abdominal pain, diarrhea, fatigue and deficiency symptoms? Many people suffer from intestinal inflammation without being aware of it as the symptoms are usually very unspecific. Inflammatory bowel diseases (IBD), which include Crohn’s disease and ulcerative colitis, affect as many as 1.6 million Americans, most of whom are diagnosed before age 35. In addition to genetic predispositions, stress, nutrition and toxic influences play an important role.

Measuring the Calprotectin concentration in the stool provides fast and reliable information about a present inflammation in the intestinal tract. Calprotectin is normally only increased in the case of an inflammatory bowel disease, but not in the case of a non-inflammatory irritable bowel syndrome. Thus, this parameter helps to differentiate whether patients suffer from a (chronic) inflammatory or non-inflammatory bowel disease.

Both, patients with an initial intestinal inflammation and those with a serious illness can be diagnosed by a Calprotectin determination in the stool sample. In addition, the markers Lysozyme and sIgA provide information about the immune function of the intestinal mucosa, Alpha 1-Antitrypsin is a marker for the increased permeability of the instestinal muscosa. Through the measurement of these four markers you get a comprehensive picture of the inflammatory state of your intestines.

The test analyzes the values of the following analytes:

  • Calprotectin
  • Lysozyme
  • Alpha 1-Antitrypsin
  • sIgA

Our Enhanced Intestinal Inflammation Check measures the important parameters Calprotectin, Lysozyme, Alpha 1-Antitrypsin and sIgA in the stool. These markers serve to detect early stages of inflammatory bowel disease quickly and reliably to then provide patients with efficient, advanced diagnostics and therapy. In addition, these parameters optimize the follow-up of chronic inflammatory bowel diseases.

How does it work?

You collect the samples at home, send them back to us and we will provide you with your level of each analyte and whether your level falls within the reference ranges for your age. In addition to that, the results include graphs showing whether your are in the “green” (=normal/healthy) or “red” (=too high/low) area, making it easy to understand the results.

What will my results tell me?

Your results will provide detailed information about whether your Calprotectin, Lysozyme, Alpha 1-Antitrypsin and sIgA levels are normal, low, or high compared to reference ranges in your age group. You can then discuss the results with your doctor or health practitioner, who can give you further guidance and treatment recommendations.

What guidance will I get along with my results?

We always recommend the discussion of the mailed results with your doctor or practitioner. Besides, further information is available on our website, especially in the different test categories, under “health conditions” and the FAQs. Still have questions? Then you can contact us by phone at +44 (0)20 3286 6316 or mail at contact@verisana.co.uk.

Test measures
For the Enhanced Intestinal Inflammation Check we analyse:
  • Lysozyme
  • Calprotectin
  • Alpha 1-Antitrypsin
  • SIgA
Lysozyme

Lysozyme is a component of nonspecific body defense and thus significantly involved in the maintenance of the mucosal barrier capacity and integrity. Lysozyme is formed by granulocytes, monocytes and macrophages and released into the intestinal lumen as part of the inflammatory response.

Calprotectin

Calprotectin is considered equivalent to the activity of granulocytes in centers of inflammation. It plays an important role in the diagnosis of inflammatory bowel diseases.

Alpha 1-Antitrypsin

Alpha 1-antitrypsin is an acute phase protein which is synthesized in the liver and in intestinal cells. In the presence of inflammation it reduces the damage to healthy tissue. Since Alpha 1-antitrypsin is not significantly cleaved or resorbed, Alpha 1-Antitrypsin is more likely to be detected in inflammations with an increased permeability of the intestinal mucosa.

SIgA

Secretory IgA is a parameter for both the state of the gut-associated immune system (GALT) and the permeability of the intestinal mucosa. That is to say it is partly responsible for a controlled mass transfer through the mucosa. Decreased sIgA values ​​indicate decreased activity of the mucosa-associated immune system and may be associated with increased permeability. Increased secretory IgA indicates an increased immunological activity of the intestinal mucosa. Possible causes can be: local inflammatory processes, allergic processes in the intestinal mucosa, chronic inflammation in the intestinal area, disorders of the defense performance.

Symptoms
Symptoms the Enhanced Intestinal Inflammation Check is suitable for:
  • Diarrhea
  • Light fever
  • Weight loss
  • Stomach pain
  • Stomach cramps
  • Exhaustion
  • Joint and muscle pain
  • Deficiency symptoms
  • Nausea and vomiting
  • Painful bowel movement
Sample collection guide
General

Please read the following instructions in detail, before starting with the sample collection.

 

Please download the instructions here

Sample report
The sample report

Below you will find the sample report for the Enhanced Intestinal Inflammation Check.

Download sample report

aaBewertungen
Comments
  1. Troy
    October 12, 2019

    The results are detailed and very informative as they include several graphs.

  2. Vivian H.
    July 11, 2019

    Test is a little pricey but I think it’s worth it as it measures all the important analytes. So it’s ok.

  3. Thomas
    December 29, 2018

    I had sooo many problems, so many symptoms that I did not understand. Verisana somehow gave me hope and helped me to find the real cause for my symptoms. Now I know where to start and that I dont have to live with those symptoms my whole life.

  4. Leona
    October 23, 2018

    I’m suffering from ulcerative colitis and did this test for a check up. Super easy and convenient.

  5. Sidney
    August 9, 2018

    Chose this test instead of the cheaper Calprotectin & Lysozyme test cause my doctor said Alpha 1-Antitrypsin was important as well. Results were easy to understand.

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Any Questions?

Here are some of the most frequently asked questions regarding this test. Your question is missing? Please contact us at:

What is the difference to the Calprotectin & Lysozyme Inflammation Check?

2 additional values ​​are determined for the Enhanced Intestinal Inflammation Check. The marker sIgA provides information about the immune function of the intestinal mucosa and alpha-1-antitrypsin is a marker for the increased permeability of the intestinal mucosa. By measuring all four inflammation markers, you get a more complete picture of the inflammatory status of your gut.

Why do intestinal inflammations often go undetected for a long time?

The reason for this are the unspecific symptoms. In 2015, an estimated 1.3% of US adults (3 million) reported being diagnosed with IBD (inflammatory bowel diseases). The number of unreported cases is probably significantly higher due to the difficult diagnosis.

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