Histamine Intolerance Test - Verisana Lab

Histamine Intolerance Test

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With the Histamine Intolerance Test, we determine your diaminooxidase level using a simple blood test.

The enzyme diaminooxidase ( DAO) plays a crucial role in the breakdown of histamine.
If this enzyme is not sufficiently present, the body cannot properly break down the histamine that has been supplied, for example, through food.

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  • Details
  • Test measures
  • Symptoms
  • Sample collection guide
  • Sample report
  • Reviews
Details
Who should take the test?

Approximately 1% of Europeans suffer from histamine intolerance. Histamine is a substance produced by the body itself, however, in higher quantities it can also be harmful to the body. Histamine intolerance is a food intolerance acquired in the course of life, which often manifests itself after the consumption of certain foods in pseudoallergic reactions such as stomach cramps, diarrhea, vomiting, respiratory problems, headaches and cardiovascular problems.

The enzyme diamine oxidase (DAO) plays a crucial role in the breakdown of histamine.
If this enzyme is not sufficiently present, the body cannot properly break down the histamine that has been supplied, for example, through food.

The advantage of measuring diaminooxidase is that it provides very reliable results on histamine intolerance. The histamine value can also be determined in the stool, but the value there can be elevated (by histamine-rich foods) without having problems with the breakdown of histamine. However, if the DAO enzyme in the blood is too low, this means that the body actually has problems breaking down histamine-rich foods.

How does it work?

You collect the sample at home, send it back to us and we send you your result with information about your diaminooxidase level. You will find out if your values are within the normal range or if there is a deficiency.

Please note that you should not be on a low histamine diet prior to testing. Otherwise, a false negative result could occur. For this reason, it is important to not be on a diet low in histamine for at least 10-14 days before taking the sample.

What guidance will I get along with my results?

Your report will contain detailed information about your diaminooxidase level and whether it is normal or too low (compared to the respective reference range for your age group). You can then discuss these results with your doctor who can advise you on how to proceed and on the various therapy options.

Although we do not offer medical advice ourselves, we will gladly assist you in finding a suitable therapist in your area. Besides, further information is available on our website, especially in the different test categories, under “health conditions” and the FAQs. Still have questions? Then you can contact us by at contact@verisana.co.uk.

How is my privacy protected?

Samples for our tests are collected in the privacy of your own home. We and our partner laboratories (who may be contracted by us to conduct some or all analyses of your test) take customer privacy very seriously. Only you will have access to this information and we will not share your information with any not authorized third party. All samples are disposed of following analysis.

Test measures
For the Histamine Intolerance Test we analyze:
  • Diamine oxidase
Diamine oxidase

The enzyme diamine oxidase (DAO) plays a crucial role in the breakdown of histamine.

With reduced activity of the enzyme DAO, histamine accumulates in the blood and can thus cause various symptoms such as:

– allergic skin reactions (hives)
– respiratory problems
– diarrhea, vomiting, nausea
– headache
– blocked or runny nose
– palpitations

Foods that can be problematic for histamine intolerance:

– long-aged cheese
– sausages
– alcohol
– nuts
– tomato, eggplant, spinach
– citrus fruits
– Additives in food

Symptoms
Symptoms the Histamine Intolerance Test is suitable for:
  • allergic skin reactions (hives)
  • respiratory problems
  • diarrhea, vomiting, nausea
  • headache
  • blocked or runny nose
  • palpitations
Sample collection guide
General

Please read the following instructions in detail, before starting with the sample collection.

Please download the instructions here

Sample report
The sample report

Below you will find the sample report for the Histamine Intolerance Test.

Download sample report

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Any Questions?

Here are some of the most frequently asked questions regarding this test. Your question is missing? Please contact us at:

Is histamine only found in certain foods or food groups?

No, histamine is found in almost all foods to some extent. Unfortunately, especially histamine-containing foods also run through all food groups, whether vegetables, cheese, sausages, fish or alcohol. Therefore, a low-histamine diet requires in-depth research.

Will the histamine intolerance test also show a reaction if I eat a histamine-free diet?

No, you should consume histamine in the days before the sample is taken in order to obtain a reliable result.

What are biogenic amines and histamine liberators?

In the case of histamine intolerance, you should not only avoid histamine-rich foods at the beginning, but also those that influence the activity of the enzyme DAO (so-called biogenic amines) and so-called histamine liberators. Histamine liberators release the body's own histamine stored by the body. Biogenic amines are found, for example, in walnuts, cashews, raw milk cheese and fish. Histamine liberators include: Beans, legumes, tomato, pineapple, citrus fruits, strawberries or cocoa.

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